Article
Susceptibility of multidrug-resistant human leukemia cell lines to human interleukin 2-activated killer cells.
Cancer research - 1 Nov 1990
Kimmig A, Gekeler V, Neumann M, Frese G, Handgretinger R, Kardos G, Diddens H, Niethammer D
Abstract excerpt
Considering the possibility to overcome drug resistance by other treatment strategies than chemotherapy we investigated the susceptibility of three independently selected multidrug-resistant sublines of the T-lymphoblastoid leukemic cell line CCRF-CEM to lymphokine-activated killer (LAK) cells. W...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Antigens, CD7
- Antigens, Differentiation
- Antigens, Differentiation, T-Lymphocyte
- Drug Resistance
- Gene Expression Regulation, Neoplastic
- Histocompatibility Antigens
- Humans
- Immunotherapy, Adoptive
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Leukemia
- Leukocyte Common Antigens