Article
Increased susceptibility to lymphokine activated killer (LAK) lysis of relapsing vs. newly diagnosed acute leukemic cells without changes in drug resistance or in the expression of adhesion molecules.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Feb 1992
Arienti F, Gambacorti-Passerini C, Borin L, Rivoltini L, Orazi A, Pogliani E M, Corneo G, Parmiani G
Abstract excerpt
The NK and LAK activity of peripheral blood lymphocytes of leukemic patients as well as the susceptibility of their acute myeloid (AML) and lymphoblastic (ALL) leukemia cells to autologous and allogeneic LAKs were examined. In addition, neoplastic cells at diagnosis and at relapse were compared in the same patients for several features, including in vitro susceptibility to LAKs and to the drugs used in the...
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