Increased susceptibility to lymphokine activated killer (LAK) lysis of relapsing vs. newly diagnosed acute leukemic cells without changes in drug resistance or in the expression of adhesion molecules.

doi:10.1093/oxfordjournals.annonc.a058133

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Article

Increased susceptibility to lymphokine activated killer (LAK) lysis of relapsing vs. newly diagnosed acute leukemic cells without changes in drug resistance or in the expression of adhesion molecules.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Feb 1992

Arienti F, Gambacorti-Passerini C, Borin L, Rivoltini L, Orazi A, Pogliani E M, Corneo G, Parmiani G

Abstract excerpt

The NK and LAK activity of peripheral blood lymphocytes of leukemic patients as well as the susceptibility of their acute myeloid (AML) and lymphoblastic (ALL) leukemia cells to autologous and allogeneic LAKs were examined. In addition, neoplastic cells at diagnosis and at relapse were compared i...

Topics

Adult
Antigens, Differentiation
Cell Adhesion Molecules
Drug Resistance
HLA Antigens
Humans
Killer Cells, Lymphokine-Activated
Leukemia, Erythroblastic, Acute
Leukemia, Monocytic, Acute
Leukemia, Myeloid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Myeloid, Acute

Leukemia, Myelomonocytic, Acute

Leukemia, Promyelocytic, Acute

Phenotype

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Receptors, Interleukin-2

Sensitivity and Specificity

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1606087
DOI: 10.1093/oxfordjournals.annonc.a058133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1606087-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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