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Article

Detection of human leukemia cells with multidrug-resistance phenotype using multilabeling with fluorescent dyes.

Anticancer research - 1 Jan 2000

Lautier D, Lahmy S, Canitrot Y, Vigo J, Viallet P, Salmon J M

Abstract excerpt

Reduced accumulation of multiple drugs is a characteristic of cells overexpressing P-glycoprotein. This phenotype is referred to as multidrug-resistance (MDR). A protocol based on reduced accumulation of fluorescent dyes is proposed for discriminating MDR cells in cell populations. The combination of three fluorescent dyes, Hoechst 33342, rhodamine 123 and Nile red, with different intracellular targets, has been...

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PMID: 8239535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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