Article
Multiple tumor types may originate from bone marrow-derived cells.
Neoplasia (New York, N.Y.) - 1 Sept 2006
Liu Chunfang, Chen Zhongwei, Chen Zhihong, Zhang Tao, Lu Yuan
Abstract excerpt
It was believed that tumors originated from the transformation of their tissue-specific stem cells. However, bone marrow-derived cells (BMDCs), which possess an unexpected degree of plasticity and often reside in other tissues, might also represent a potential source of malignancy. To study whether BMDCs play a role in the source of other tumors, BMDCs from mice were treated with 3-methycholanthrene until...
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