Multipotent marrow stromal cell line is able to induce hematopoiesis in vivo.

doi:10.1002/jcp.1041510125

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Multipotent marrow stromal cell line is able to induce hematopoiesis in vivo.

Journal of cellular physiology - 1 Apr 1992

Umezawa A, Maruyama T, Segawa K, Shadduck R K, Waheed A, Hata J

Abstract excerpt

Several murine marrow stromal cells were established from murine bone marrow cultures. Stromal cell lines transfected with a tumor-inducing polyoma virus middle T antigen (MTAg) were inoculated into nude mice subcutaneously. KUSA-MTAg cells, one of these cell lines, led to the rapid local development of bone marrow consisting of trilineage hematopoietic cells and bone; other cell lines produced spindle cell...

Topics

Adipose Tissue
Alkaline Phosphatase
Animals
Antigens, Polyomavirus Transforming
Azacitidine
Bone Marrow
Bone Marrow Cells
Cell Differentiation
Cell Line
Cells, Cultured
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hemangiosarcoma

Hematopoiesis

Hematopoietic Stem Cells

Mice

Mice, Inbred BALB C

Mice, Inbred C3H

Mice, Nude

Source

Open in PubMed

Identifiers

PMID: 1373147
DOI: 10.1002/jcp.1041510125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1373147-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multipotent marrow stromal cell line is able to induce hematopoiesis in vivo.PMID 1373147Read ↗

Marrow Stromal Cells as Stem Cells for Nonhematopoietic TissuesSemantic proximity Read ↗

Bone marrow stromal cells as targets for gene therapy.Semantic proximity Read ↗

Mesenchymal stem cells.Semantic proximity Read ↗

Human Multipotent Mesenchymal Stromal Cells from Distinct Sources Show Different In Vivo Potential to Differentiate into Muscle Cells When Injected in Dystrophic MiceSemantic proximity Read ↗

A novel tumor cell line cloned from mutated human embryonic bone marrow mesenchymal stem cells.Semantic proximity Read ↗

Multiple tumor types may originate from bone marrow-derived cells.Semantic proximity Read ↗

Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical modelSemantic proximity Read ↗

Multilineage gene expression in human bone marrow stromal cells as evidenced by single-cell microarray analysis.Semantic proximity Read ↗

Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation.Semantic proximity Read ↗

Genetically transforming human mesenchymal stem cells to sarcomas: changes in cellular phenotype and multilineage differentiation potential.Semantic proximity Read ↗

The influence of hypoxia on the differentiation capacities and immunosuppressive properties of clonal mouse mesenchymal stromal cell lines.Semantic proximity Read ↗

Oligopotent mesenchymal stem cell-like clone becomes multinucleated following phorbol ester, TPA stimulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.