Article
Multipotent marrow stromal cell line is able to induce hematopoiesis in vivo.
Journal of cellular physiology - 1 Apr 1992
Umezawa A, Maruyama T, Segawa K, Shadduck R K, Waheed A, Hata J
Abstract excerpt
Several murine marrow stromal cells were established from murine bone marrow cultures. Stromal cell lines transfected with a tumor-inducing polyoma virus middle T antigen (MTAg) were inoculated into nude mice subcutaneously. KUSA-MTAg cells, one of these cell lines, led to the rapid local development of bone marrow consisting of trilineage hematopoietic cells and bone; other cell lines produced spindle cell...
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