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Article

Osteosarcoma cells differentiate into phenotypes from all three dermal layers.

Clinical orthopaedics and related research - 1 Oct 2011

Russinoff Scott, Miran Sara, Gowda Ashok L, Lucas Paul A

Abstract excerpt

BACKGROUND: Osteosarcomas are the most common solid malignant bone tumors, but little is known of their origin. The embryonal rest hypothesis views cancer cells as arising from committed progenitor stem cells in each tissue. Adult tissue contains primitive stem cells that retain the ability to di...

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Identifiers

PMID: 21678097
DOI: 10.1007/s11999-011-1946-3
PMCID: PMC3171540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21678097-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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