Article
Cyclic adenosine monophosphate modulates cell morphology and behavior of a cultured renal epithelial.
Pediatric nephrology (Berlin, Germany) - 1 Jul 1990
Amsler K
Abstract excerpt
The role of cyclic adenosine monophosphate (cAMP) dependent protein kinase (PKA) in modulating functions of differentiated renal cells is well established. Its importance in controlling their growth and differentiation is less clear. We have used somatic cell genetic techniques to probe the role of PKA in controlling morphology and behavior of a renal epithelial cell line, LLC-PK1, which acquires many properties...
Topics
- 1-Methyl-3-isobutylxanthine
- Animals
- Cell Division
- Cell Line
- Chlorocebus aethiops
- Clone Cells
- Cyclic AMP
- Epithelial Cells
- Hexoses
- Kidney
- Mutation
- Protein Kinases
