Article
A system to select for mutant LLC-PK1 cells affected in cAMP mediated hormonal response using a photoactivatable analogue of vasopressin.
Journal of receptor research - 1 Jan 1990
Luzius H, Jans D A, Fahrenholz F
Abstract excerpt
The photoreactive analogue of vasopressin, [1-(3-mercapto)propionic acid, 8-(N6-4-azidophenyl-amidino)lysine] vasopressin (apa-LVP) could be used to elicit stimulation of cAMP production in LLC-PK renal epithelial cells, detectable up to 24 h after photoactivation by flash photolysis. This is in...
Topics
- Adenylyl Cyclases
- Animals
- Cells, Cultured
- Cyclic AMP
- Drug Resistance
- Enzyme Activation
- Epithelial Cells
- Fibrinolytic Agents
- Kidney
- Lypressin
- Mutation
- Phenotype
- Photochemistry
- Plasminogen Activators
- Stimulation, Chemical
- Swine
- Urokinase-Type Plasminogen Activator
- Vasopressins
