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Article

Regulation of lung epithelial cell morphology by cAMP-dependent protein kinase type I isozyme.

American journal of physiology. Lung cellular and molecular physiology - 1 Jun 2001

Porter S E, Dwyer-Nield L D, Malkinson A M

Abstract excerpt

Cell shape is mediated in part by the actin cytoskeleton and the actin-binding protein vinculin. These proteins in turn are regulated by protein phosphorylation. We assessed the contribution of cAMP-dependent protein kinase A isozyme I (PKA I) to lung epithelial morphology using the E10/E9 sibling cell lines. PKA I concentration is high in flattened, nontumorigenic E10 cells but low in their round E9...

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Identifiers

PMID: 11350809
DOI: 10.1152/ajplung.2001.280.6.L1282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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