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Article

cAMP-dependent protein kinase and proliferation differ in normal and polycystic kidney epithelia.

American journal of physiology. Cell physiology - 1 Apr 2002

Marfella-Scivittaro Carmela, Quiñones Andrea, Orellana Stephanie A

Abstract excerpt

Developmental control of cell proliferation is crucial, and abnormal principal cell proliferation may contribute to cystogenesis in polycystic kidney disease. This study investigates roles of cAMP and its primary effector, cAMP-dependent protein kinase (protein kinase A; PKA), in control of cell proliferation in filter-grown noncystic (NC) and cystic (CY)-derived principal cell cultures. These cultures had...

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Identifiers

PMID: 11880258
DOI: 10.1152/ajpcell.00122.2001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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