Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Small molecules with antimicrobial activity against <i>E. coli</i> and <i>P. aeruginosa</i> identified by high‐throughput screening

18 Sept 2006

Abstract excerpt

BACKGROUND AND PURPOSE: New antimicrobials are needed because of the emergence of organisms that are resistant to available antimicrobials. The purpose of this study was to evaluate a high-throughput screening approach to identify antibacterials against two common disease-causing bacteria, and to determine the frequency, novelty, and potency of compounds with antibacterial activity. EXPERIMENTAL APPROACH: A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial agents and applications
Share to Computational Drug Discovery Methods
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16981005
DOI: 10.1038/sj.bjp.0706873

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Small molecules with antimicrobial activity against <i>E. coli</i> and <i>P. aeruginosa</i> identified by high‐throughput screeningPMID 16981005Read ↗

Identification of anti-pathogenic activity among <i>in silico</i> predicted small molecule inhibitors of <i>Pseudomonas aeruginosa</i> LasR or Nitric Oxide Reductase (NOR)Semantic proximity Read ↗

High-content assessment of <i>Pseudomonas aeruginosa</i> bacteriophage efficacy reveals host genetic factors involved in phage specificitySemantic proximity Read ↗

Discovery of Antibiotic ( <i>E</i> )-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3 <i>H</i> )-oneSemantic proximity Read ↗

Polynuclear ruthenium complexes are effective antibiotics against <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative BacteriaSemantic proximity Read ↗

Development of Potent Inhibitors of Pyocyanin Production in<i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa.Semantic proximity Read ↗

Small Molecules That Modulate Quorum Sensing and Control Virulence in<i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

Repurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant <i>Pseudomonas aeruginosa</i> and <i>Acinetobacter baumannii</i>Semantic proximity Read ↗

<i>In vitro</i> and <i>in vivo</i> activity profiles of broad-spectrum bacterial ATP synthase inhibitorsSemantic proximity Read ↗

Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of <i>Pseudomonas aeruginosa</i> Virulence PhenotypesSemantic proximity Read ↗

Current Screening Methodologies in Drug Discovery for Selected Human DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.