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Development of Potent Inhibitors of Pyocyanin Production in<i>Pseudomonas aeruginosa</i>

18 Jan 2015

Abstract excerpt

The development of new approaches for the treatment of antimicrobial-resistant infections is an urgent public health priority. The Pseudomonas aeruginosa pathogen, in particular, is a leading source of infection in hospital settings, with few available treatment options. In the context of an effort to develop antivirulence strategies to combat bacterial infection, we identified a series of highly effective small...

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PMID: 25597392
DOI: 10.1021/jm5015082

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