Small Molecules That Modulate Quorum Sensing and Control Virulence in<i>Pseudomonas aeruginosa</i>

Abstract excerpt

Bacteria use small molecule signals to access their local population densities in a process called quorum sensing (QS). Once a threshold signal concentration is reached, and therefore a certain number of bacteria have assembled, bacteria use QS to change gene expression levels and initiate behaviors that benefit the group. These group processes play central roles in both bacterial virulence and symbiosis and can...

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