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High-content assessment of <i>Pseudomonas aeruginosa</i> bacteriophage efficacy reveals host genetic factors involved in phage specificity

2025-04-03

Abstract excerpt

Pseudomonas aeruginosa infects immunocompromised and hospitalized individuals, resulting in over 500,000 annual deaths. With emerging multidrug resistance and stagnating antibiotic development, alternative antimicrobials are desperately needed. Bacteriophages (phages) offer a promising, effective, and safe alternative. We developed and optimized a high-content liquid assay screen and a stringent assessment of effi...

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Literature Corpus work
8ad59e44-f117-58b9-a1cb-a5863d60e72a
DOI
10.1101/2025.04.03.646983
Open publication

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High-content assessment of <i>Pseudomonas aeruginosa</i> bacteriophage efficacy reveals host genetic factors involved in phage specificityDOI 10.1101/2025.04.03.646983
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