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Article

Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway.

DNA repair - 4 Jan 2007

Daviet Stéphane, Couvé-Privat Sophie, Gros Laurent, Shinozuka Kazuo, Ide Hiroshi, Saparbaev Murat, Ishchenko Alexander A

Abstract excerpt

Most common point mutations occurring spontaneously or induced by ionizing radiation are C-->T transitions implicating cytosine as the target. Oxidative cytosine derivatives are the most abundant and mutagenic DNA damage induced by oxidative stress. Base excision repair (BER) pathway initiated by DNA glycosylases is thought to be the major pathway for the removal of these lesions. However, in alternative...

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Identifiers

PMID: 16978929
DOI: 10.1016/j.dnarep.2006.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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