Article
Fetal rhd genotyping from maternal plasma in a population with a highly diverse ethnic background.
Revista da Associacao Medica Brasileira (1992) - 1 Jan 2000
Machado Isabela Nelly, Castilho Lilian, Pellegrino Jordão, Barini Ricardo
Abstract excerpt
OBJECTIVE: To establish the performance of conventional PCR as a noninvasive method for fetal genotyping, by free fetal DNA analysis of distinct RHD regions from maternal plasma, in a population of a diverse ethnic origin. METHODS: We conducted a validity of the diagnostic test by analyzing 81 plasma samples from RhD-negative Brazilian pregnant women, from 4 to 41 gestational weeks. We tested for exon 10 and...
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