Article
Noninvasive fetal RHD genotyping from maternal plasma in an admixed Brazilian population.
Genetics and molecular research : GMR - 7 Feb 2014
Schmidt L C, Cabral A C V, Faria M A, Monken F, Tarazona-Santos E, Martins M L
Abstract excerpt
We evaluated the efficacy of noninvasive fetal Rhesus D (RHD) genotyping from maternal plasma in a highly admixed population. Fifty-five blood samples from RhD-negative pregnant women from Brazil were processed for extraction of cell-free plasma DNA. Real-time PCR was performed to amplify segments of exons 5 and 7 from the RHD gene, as well as for detection of the SRY gene to confirm the presence of fetal DNA....
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