Article
Noninvasive determination of fetal rh blood group, D antigen status by cell-free DNA analysis in maternal plasma: experience in a Brazilian population.
American journal of perinatology - 1 Nov 2010
Chinen Paulo Alexandre, Nardozza Luciano Marcondes Machado, Martinhago Ciro Dresch, Camano Luiz, Daher Silvia, Pares David Baptista da Silva, Minett Thais, Araujo Júnior Edward, Moron Antonio Fernandes
Abstract excerpt
We evaluated the diagnostic accuracy of Rh blood group, D antigen (RHD) fetal genotyping, using real-time polymerase chain reaction in maternal blood samples, in a racially mixed population. We performed a prospective study conducted between January 2006 and December 2007, analyzing fetal RHD genotype in the plasma of 102 D- pregnant women by real-time polymerase chain reaction, targeting exons 7 and 10 of the...
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