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Article

The central DNA flap of the human immunodeficiency virus type 1 is important for viral replication.

Biochemical and biophysical research communications - 27 Oct 2006

De Rijck Jan, Debyser Zeger

Abstract excerpt

Reverse transcription of the human immunodeficiency virus type 1 is characterized by the formation of a DNA flap at the center of the viral cDNA in between the central polypurine tract (cPPT) and the central termination sequence (CTS). The importance of the DNA flap for HIV-1 replication has been questioned, whereas its importance for lentiviral vector performance is well accepted. To investigate this...

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Identifiers

PMID: 16962998
DOI: 10.1016/j.bbrc.2006.08.141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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