Article
The HIV-1 DNA flap stimulates HIV vector-mediated cell transduction in the brain.
Nature biotechnology - 1 May 2001
Zennou V, Serguera C, Sarkis C, Colin P, Perret E, Mallet J, Charneau P
Abstract excerpt
During HIV-1 reverse transcription, central initiation of the plus-strand DNA at the central polypurine tract (cPPT) and central termination at the central termination sequence (CTS) lead to the formation of a three-stranded DNA structure: the HIV-1 central DNA flap. We recently reported that the...
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