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Article

Design of HIV Vectors for Efficient Gene Delivery into Human Hematopoietic Cells

1 Apr 2002

Abstract excerpt

Vectors derived from human immunodeficiency virus (HIV) hold promise for efficient gene delivery into human hematopoietic cells. In this study, HIV vectors containing different combinations of cis-acting elements, including the HIV central flap sequence, and the woodchuck posttranscriptional regulatory element (WPRE) in combination with two different promoters, were used to transduce primary human lymphocytes and...

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PMID: 11945076
DOI: 10.1006/mthe.2002.0558

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