Article
Complex effects of foamy virus central purine-rich regions on viral replication.
Virology - 30 Mar 2008
Peters Katrin, Barg Nicole, Gärtner Kathleen, Rethwilm Axel
Abstract excerpt
Similar to the lentiviruses family of retroviruses, foamy viruses (FVs) contain purine-rich sequences located in the center of the genome. Their function on viral replication or vector transfer remains elusive, although dual initiation of plus-strand reverse transcription has been suggested. To elucidate the physical nature of the central region of the prototype FV (PFV) genome, we performed 3' and 5' RACE...
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