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Article

A flexible Bayesian framework for modeling haplotype association with disease, allowing for dominance effects of the underlying causative variants.

American journal of human genetics - 1 Oct 2006

Morris Andrew P

Abstract excerpt

Multilocus analysis of single-nucleotide-polymorphism (SNP) haplotypes may provide evidence of association with disease, even when the individual loci themselves do not. Haplotype-based methods are expected to outperform single-SNP analyses because (i) common genetic variation can be structured into haplotypes within blocks of strong linkage disequilibrium and (ii) the functional properties of a protein are...

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Identifiers

PMID: 16960804
DOI: 10.1086/508264
PMCID: PMC1592560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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