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Article

Protection from inflammatory disease in insulin resistance: the role of mannan-binding lectin.

Diabetologia - 1 Oct 2006

Fernández-Real J M, Straczkowski M, Vendrell J, Soriguer F, Pérez Del Pulgar S, Gallart L, López-Bermejo A, Kowalska I, Manco M, Cardona F, García-Gil M M, Mingrone G, Richart C, Ricart W, Zorzano A

Abstract excerpt

AIMS/HYPOTHESIS: Decreased sensing of the innate immune system may lead to chronic activation of the inflammatory cascade. We hypothesised that mannan-binding lectin (MBL) deficiency may confer risk of obesity and insulin resistance. MATERIALS AND METHODS: We performed a cross-sectional study of MBL protein concentration (n=434) and MBL2 gene mutations (exon 1) (n=759) in association with obesity, markers of...

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Source

Identifiers

PMID: 16955210
DOI: 10.1007/s00125-006-0381-6

Genes

MBL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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