Article
Increased all-cause mortality in patients with type 1 diabetes and high-expression mannan-binding lectin genotypes: a 12-year follow-up study.
Diabetes care - 1 Oct 2015
Østergaard Jakob A, Thiel Steffen, Lajer Maria, Steffensen Rudi, Parving Hans-Henrik, Flyvbjerg Allan, Rossing Peter, Tarnow Lise, Hansen Troels K
Abstract excerpt
OBJECTIVE: Mannan-binding lectin (MBL) is a complement-activating carbohydrate-recognizing molecule associated with diabetic nephropathy. MBL is associated with all-cause mortality in type 2 diabetes, but whether MBL is associated with mortality in type 1 diabetes remains unknown. We therefore aimed to investigate this. RESEARCH DESIGN AND METHODS: We studied an existing 12-year prospective cohort with type 1...
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