Article
Association between mannose-binding lectin and vascular complications in type 1 diabetes.
Diabetes - 1 Jun 2004
Hansen Troels K, Tarnow Lise, Thiel Steffen, Steffensen Rudi, Stehouwer Coen D, Schalkwijk Casper G, Parving Hans-Henrik, Flyvbjerg Allan
Abstract excerpt
Complement activation and inflammation have been suggested in the pathogenesis of diabetic vascular lesions. We investigated serum mannose-binding lectin (MBL) levels and polymorphisms in the MBL gene in type 1 diabetic patients with and without diabetic nephropathy and associated macrovascular complications. Polymorphisms in the MBL gene and serum MBL levels were determined in 199 type 1 diabetic patients with...
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