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Mannose-binding lectin and risk of infections in type 2 diabetes: A Danish cohort study.

Journal of diabetes and its complications - 1 May 2021

Gedebjerg Anne, Thomsen Reimar Wernich, Kjaergaard Alisa Devedzic, Steffensen Rudi, Nielsen Jens Steen, Rungby Jørgen, Friborg Søren Gunnar, Brandslund Ivan, Thiel Steffen, Beck-Nielsen Henning, Sørensen Henrik Toft, Hansen Troels Krarup, Bjerre Mette

Abstract excerpt

AIMS: In individuals at increased risk of infections, e.g., patients with type 2 diabetes, low MBL may have detrimental effects. We used the Mendelian randomization principle to examine whether genetically low MBL is a risk factor for developing infections in patients with type 2 diabetes. METHODS: Serum MBL (n = 7305) and MBL genotype (n = 3043) were determined in a nationwide cohort of patients with new type 2...

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PMID: 33627253
DOI: 10.1016/j.jdiacomp.2021.107873

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