Mannose-binding lectin activates the nuclear factor-κB and renal inflammation in the progression of diabetic nephropathy.

doi:10.1096/fj.202101852R

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Article

Mannose-binding lectin activates the nuclear factor-κB and renal inflammation in the progression of diabetic nephropathy.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2022

Ma Yanhong, Cai Fanghao, Huang Xiaohan, Wang Huijing, Yu Binfeng, Wang Junni, Nie Wanyun, Cai Kedan, Yang Yi, Chen Jianghua, Xiao Liang, Han Fei

Abstract excerpt

Increased serum mannose-binding lectin (MBL) level has been proven to correlate with the development of diabetic nephropathy (DN). Here, we aim to find the role and mechanism of MBL involved in the progression of DN. Patients with DN were recruited and divided into two groups according to different rs1800450 genotypes of the MBL2 gene, and inflammatory profiles in monocytes/macrophages were compared between the...

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PMID: 35195918
DOI: 10.1096/fj.202101852R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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