Article
A model for cell-surface-exposed carbohydrate moieties suitable for structural studies by NMR spectroscopy.
Chembiochem : a European journal of chemical biology - 1 Nov 2006
Mares Jiri, Müller Jan U, Skirgailiene Audrone, Neumoin Alexey, Bewley Carole A, Schmidt Richard R, Zerbe Oliver
Abstract excerpt
In the present study a synthetic glycolipid system is presented that can be readily incorporated into phospholipid micelles and that allows the study of cell-surface-exposed carbohydrate units by high-resolution NMR techniques. Here, we present an efficient route for the synthesis of glycolipid compounds that contain mannose, mannobiose, or mannotriose coupled either directly to an alkyl chain or through a...
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