Article
The role of the membrane-spanning domain and stalk region of N-acetylglucosaminyltransferase I in retention, kin recognition and structural maintenance of the Golgi apparatus in HeLa cells.
Journal of cell science - 1 Jul 1996
Nilsson T, Rabouille C, Hui N, Watson R, Warren G
Abstract excerpt
Using a series of chimeric and truncated N-acetylglucosaminyltransferase I (NAGT I) molecules we have shown that part of the lumenal stalk region is both necessary and sufficient for kin recognition of mannosidase II and retention in the Golgi stack. The membrane-spanning domain was not required...
Topics
- Amino Acid Sequence
- Base Sequence
- Biological Transport
- Cell Membrane
- DNA, Recombinant
- Golgi Apparatus
- HeLa Cells
- Humans
- Leucine
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- N-Acetylglucosaminyltransferases