Article
TOS9 regulates white-opaque switching in Candida albicans.
Eukaryotic cell - 1 Oct 2006
Srikantha Thyagarajan, Borneman Anthony R, Daniels Karla J, Pujol Claude, Wu Wei, Seringhaus Michael R, Gerstein Mark, Yi Song, Snyder Michael, Soll David R
Abstract excerpt
In Candida albicans, the a1-alpha2 complex represses white-opaque switching, as well as mating. Based upon the assumption that the a1-alpha2 corepressor complex binds to the gene that regulates white-opaque switching, a chromatinimmunoprecipitation-microarray analysis strategy was used to identify 52 genes that bound to the complex. One of these genes, TOS9, exhibited an expression pattern consistent with a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
