Article
Active mutants of the human p38alpha mitogen-activated protein kinase.
The Journal of biological chemistry - 5 Nov 2004
Diskin Ron, Askari Nadav, Capone Ricardo, Engelberg David, Livnah Oded
Abstract excerpt
Mitogen-activated protein (MAP) kinases compose a family of serine/threonine kinases that function in many signal transduction pathways and affect various cellular phenotypes. Despite the abundance of available data, the exact role of each MAP kinase is not completely defined, in part because of the inability to activate MAP kinase molecules individually and specifically. Based on activating mutations found in...
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