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Article

Ligand interaction scan (LIScan) in the study of ERK8.

Biochemical and biophysical research communications - 13 Aug 2010

Erster Oran, Seger Rony, Liscovitch Mordechai

Abstract excerpt

ERK8 is the most recent addition for the MAPK family, and its mechanism of activation and function are not yet known, mainly due to the lack of any known physiological stimulator. In this report, we describe the preparation of reagents for the use of a novel method, the ligand interaction scan (LIScan), to study the function of this protein kinase. We generated a set of mutants of ERK8, and identified inhibited...

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Identifiers

PMID: 20638370
DOI: 10.1016/j.bbrc.2010.07.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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