Article
Evaluation of MMP3 and TIMP1 as candidate genes for high myopia in young Taiwanese men.
American journal of ophthalmology - 1 Sept 2006
Liang Chung-Ling, Wang Hsin-Shih, Hung Kuo-Sheng, Hsi Edward, Sun Angel, Kuo Yi-Hui, Juo Suh-Hang Hank
Abstract excerpt
PURPOSE: We studied the relationship between high myopia and the MMP3 and TIMP1 genes. DESIGN: Case-control study. METHODS: We enrolled 150 high myopic individuals (< or = -6 diopters) and 262 controls (> or = -1.5 diopters) initially, and another 216 cases and 474 controls were enrolled for genotyping promising polymorphisms for replication. Thirteen polymorphisms were genotyped in the initial data. Logistic...
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