Article
An association study of the COL1A1 gene and high myopia in a Han Chinese population.
Molecular vision - 1 Jan 2011
Zhang Dingding, Shi Yi, Gong Bo, He Fei, Lu Fang, Lin He, Wu Zhengzheng, Cheng Jing, Chen Bin, Liao Shihuang, Ma Shi, Hu Jianbin, Yang Zhenglin
Abstract excerpt
PURPOSE: Single nucleotide polymorphisms (SNPs) in the collagen type I (COL1A1) gene have been shown to be significantly associated with high myopia in a Japanese population. This present study was conducted to investigate whether COL1A1 is associated with high myopia in a Han Chinese population. METHODS: High myopia is defined by a spherical equivalent of less than or equal to -6.00 diopter sphere and an axial...
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