Article
Contribution of TIMP3 polymorphisms to the development of preeclampsia in Han Chinese women.
Journal of assisted reproduction and genetics - 1 Oct 2015
Guo Changlong, Cao Xiaofang, Wang Qidi, Wang Guangyu, An Lisha, Du Meng, Qiu Yue, Yang Ying, Li Hui, Wang Yuting, Wang Shuo, Wang Xingyu, Ma Xu
Abstract excerpt
PURPOSE: The aim of this study was to investigate whether polymorphisms in the tissue inhibitor of metalloproteinase 3 gene (TIMP3) are associated with the risk of preeclampsia (PE) in Han Chinese women. METHODS: Nine single TIMP3 tag-single nucleotide polymorphisms were selected by Haploview and genotyped using the Sequenom method in 181 preeclamptic and 203 healthy pregnant women from eastern China. RESULTS:...
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