Article
Exclusion of transforming growth factor-beta1 as a candidate gene for myopia in the Japanese.
Japanese journal of ophthalmology - 1 Jan 2000
Hayashi Takahiko, Inoko Hidetoshi, Nishizaki Ritsuko, Ohno Shigeaki, Mizuki Nobuhisa
Abstract excerpt
PURPOSE: To determine whether single-nucleotide polymorphisms (SNPs) within the transforming growth factor-beta1 (TGF-beta1) gene are associated with high myopia in Japanese. Previous studies have indicated that the gene expression products, regulators of the TGF-beta1 gene, are involved in high myopia. METHODS: Genomic DNA samples were obtained from 330 Japanese patients with high myopia and 330 Japanese...
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