Article
Unravelling the Contribution of Matrix Metalloproteinase-3 Genotype-Phenotype to Pterygium Risk.
Cancer genomics & proteomics - 1 Jan 2026
Chen Hung-Chih, Hsia Ning-Yi, Tsai Chung-Lin, Hsia Te-Chun, Hu Pei-Shin, Wang Yun-Chi, Shih Hou-Yu, Chang Wen-Shin, Lin Jiunn-Cherng, Bau DA-Tian, Tsai Chia-Wen
Abstract excerpt
BACKGROUND/AIM: Pterygium is a fibrovascular ocular disease characterized by extracellular matrix (ECM) remodeling. Matrix metalloproteinase-3 (MMP-3), a key ECM-modulating enzyme, has been implicated to involved in pterygium progression, but its genetic marker has never been explored. This hospital-based case-control study investigated the association between MMP-3 polymorphisms and pterygium risk in a Taiwanese...
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