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Article

Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters.

British journal of clinical pharmacology - 1 Sept 2006

Vormfelde Stefan V, Schirmer Markus, Hagos Yohannes, Toliat Mohammad R, Engelhardt Sabine, Meineke Ingolf, Burckhardt Gerhard, Nürnberg Peter, Brockmöller Jürgen

Abstract excerpt

AIMS: To investigate the association between torsemide renal clearance and genetic variation in the basolaterally expressed renal organic anion transporters OAT1 and OAT3 and in the luminally situated OAT4. METHODS: We analysed 22 polymorphisms in the OAT coding genes SLC22A6, SLC22A8 and SLC22A11 and their haplotypes and measured torsemide renal clearance in 95 healthy men. In addition, the effect of torsemide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16934049
DOI: 10.1111/j.1365-2125.2006.02655.x
PMCID: PMC1885129

Genes

OAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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