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Article

Drug transport by Organic Anion Transporters (OATs).

Pharmacology & therapeutics - 1 Oct 2012

Burckhardt Gerhard

Abstract excerpt

Common to all so far functionally characterized Organic Anion Transporters (OATs) is their broad substrate specificity and their ability to exchange extracellular against intracellular organic anions. Many OATs occur in renal proximal tubules, the site of active drug secretion. Exceptions are murine Oat6 (nasal epithelium), human OAT7 (liver), and rat Oat8 (renal collecting ducts). In human kidneys, OAT1, OAT2,...

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Source

Identifiers

PMID: 22841915
DOI: 10.1016/j.pharmthera.2012.07.010

Genes

ACE
OAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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