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Article

Not lipoteichoic acid but lipoproteins appear to be the dominant immunobiologically active compounds in Staphylococcus aureus.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2006

Hashimoto Masahito, Tawaratsumida Kazuki, Kariya Hiroyuki, Kiyohara Ai, Suda Yasuo, Krikae Fumiko, Kirikae Teruo, Götz Friedrich

Abstract excerpt

Lipoteichoic acid (LTA) derived from Staphylococcus aureus is reported to be a ligand of TLR2. However, we previously demonstrated that LTA fraction prepared from bacterial cells contains lipoproteins, which activate cells via TLR2. In this study, we investigated the immunobiological activity of LTA fraction obtained from S. aureus wild-type strain, lipoprotein diacylglycerol transferase deletion (delta lgt)...

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Source

Identifiers

PMID: 16920954
DOI: 10.4049/jimmunol.177.5.3162

Genes

LTA
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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