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Lipoteichoic acid of Streptococcus gordonii as a negative regulator of human dendritic cell activation

28 Mar 2023

Abstract excerpt

Streptococcus gordonii, an opportunistic Gram-positive bacterium, causes an infective endocarditis that could be fatal to human health. Dendritic cells (DCs) are known to be involved in disease progression and immune responses in S. gordonii infection. Since lipoteichoic acid (LTA) is a representative virulence factor of S. gordonii, we here investigated its role in the activation of human DCs stimulated with...

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PMID: 37056772
DOI: 10.3389/fimmu.2023.1056949

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