Article
Host defenses against Staphylococcus aureus infection require recognition of bacterial lipoproteins.
Proceedings of the National Academy of Sciences of the United States of America - 12 Sept 2006
Bubeck Wardenburg Juliane, Williams Wade A, Missiakas Dominique
Abstract excerpt
Toll-like receptors and other immune-signaling pathways play important roles as sensors of bacterial pattern molecules, such as peptidoglycan, lipoprotein, or teichoic acid, triggering innate host immune responses that prevent infection. Immune recognition of multiple bacterial products has been viewed as a safeguard against stealth infections; however, this hypothesis has never been tested for Staphylococcus...
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