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Article

Lipoproteins in Streptococcus gordonii are critical in the infection and inflammatory responses.

Molecular immunology - 1 Sept 2018

Kim Hyun Young, Kim A Reum, Seo Ho Seong, Baik Jung Eun, Ahn Ki Bum, Yun Cheol-Heui, Han Seung Hyun

Abstract excerpt

Gram-positive bacteria such as Streptococcus gordonii causing life-threatening infective endocarditis are mainly recognized by Toll-like receptor 2 (TLR2). Lipoteichoic acid (LTA) and lipoproteins are representative TLR2 ligands that play important roles in bacterial infection and in host inflammatory responses. In the present study, we generated an LTA-deficient mutant (ΔltaS) and a lipoprotein-deficient mutant...

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Identifiers

PMID: 30176521
DOI: 10.1016/j.molimm.2018.08.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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