Article
Auxiliary role for D-alanylated wall teichoic acid in Toll-like receptor 2-mediated survival of Staphylococcus aureus in macrophages.
Immunology - 1 Feb 2010
Shiratsuchi Akiko, Shimizu Kaori, Watanabe Ikuko, Hashimoto Yumi, Kurokawa Kenji, Razanajatovo Iony M, Park Keun H, Park Hae K, Lee Bok L, Sekimizu Kazuhisa, Nakanishi Yoshinobu
Abstract excerpt
We previously reported that Staphylococcus aureus avoids killing within macrophages by exploiting the action of Toll-like receptor 2 (TLR2), which leads to the c-Jun N-terminal kinase (JNK)-mediated inhibition of superoxide production. To search for bacterial components responsible for this event...
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