Article
High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization.
Carcinogenesis - 1 Aug 2004
Nakao Kentaro, Mehta Kshama R, Fridlyand Jane, Moore Dan H, Jain Ajay N, Lafuente Amalia, Wiencke John W, Terdiman Jonathan P, Waldman Frederic M
Abstract excerpt
Array-based comparative genomic hybridization (CGH) allows for the simultaneous examination of thousands of genomic loci at 1-2 Mb resolution. Copy number alterations detected by array-based CGH can aid in the identification and localization of cancer causing genes. Here we report the results of array-based CGH in a set of 125 primary colorectal tumors hybridized onto an array consisting of 2463 bacterial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
