Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila ramshackle gene encodes a chromatin-associated protein required for cell morphology in the developing eye.

Mechanisms of development - 1 Aug 2006

D'Costa Allison, Reifegerste Rita, Sierra Scott, Moses Kevin

Abstract excerpt

We have identified ramshackle (ram) as a dominant suppressor of hedgehog loss-of-function in the developing Drosophila eye. We have characterized the gene and it encodes a double bromodomain protein with eight WD40 repeats. The Ram protein is localized predominantly to polytene chromosome interbands and is required for the transcription of some genes. ram is an essential gene and null mutants die during larval...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Shape
Share to Chromatin
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Embryo, Mammalian

Share to Embryo, Nonmammalian

Share to Hedgehog Proteins

Source

Identifiers

PMID: 16904300
DOI: 10.1016/j.mod.2006.06.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila ramshackle gene encodes a chromatin-associated protein required for cell morphology in the developing eye.PMID 16904300Read ↗

Overexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3' regulatory and coding components, respectively, of the Dlmo gene.Semantic proximity Read ↗

Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression.Semantic proximity Read ↗

SCAR is a primary regulator of Arp2/3-dependent morphological events in DrosophilaSemantic proximity Read ↗

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.Semantic proximity Read ↗

eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins.Semantic proximity Read ↗

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis.Semantic proximity Read ↗

Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4.Semantic proximity Read ↗

Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila.Semantic proximity Read ↗

Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins.Semantic proximity Read ↗

Discs large 5, an Essential Gene in Drosophila, Regulates Egg Chamber Organization.Semantic proximity Read ↗

Genetic screens for enhancers of brahma reveal functional interactions between the BRM chromatin-remodeling complex and the delta-notch signal transduction pathway in Drosophila.Semantic proximity Read ↗

Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.