Overexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3' regulatory and coding components, respectively, of the Dlmo gene.

doi:10.1093/genetics/150.1.283

Article

Overexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3' regulatory and coding components, respectively, of the Dlmo gene.

Genetics - 1 Sept 1998

Shoresh M, Orgad S, Shmueli O, Werczberger R, Gelbaum D, Abiri S, Segal D

Abstract excerpt

LIM domains function as bridging modules between different members of multiprotein complexes. We report the cloning of a LIM-containing gene from Drosophila, termed Dlmo, which is highly homologous to the vertebrate LIM-only (LMO) genes. The 3' untranslated (UTR) of Dlmo contains multiple motifs...

Topics

Animals
Base Sequence
DNA
Drosophila
Drosophila Proteins
Female
Homeodomain Proteins
Male
Molecular Sequence Data
Mutation
Phenotype
Regulatory Sequences, Nucleic Acid
Restriction Mapping

Overexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3' regulatory and coding components, respectively, of the Dlmo gene.

Abstract excerpt

Topics

Discuss the evidence