Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins.

doi:10.1093/genetics/155.3.1231

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Article

Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins.

Genetics - 1 Jul 2000

Aguilera M, Oliveros M, Martínez-Padrón M, Barbas J A, Ferrús A

Abstract excerpt

We report the identification and functional characterization of ariadne-1 (ari-1), a novel and vital Drosophila gene required for the correct differentiation of most cell types in the adult organism. Also, we identify a sequence-related gene, ari-2, and the corresponding mouse and human homologues of both genes. All these sequences define a new protein family by the Acid-rich, RING finger, B-box, RING finger,...

Topics

Alleles
Amino Acid Motifs
Animals
Cloning, Molecular
Conserved Sequence
Drosophila
Drosophila Proteins
Female
Genes
Humans
Insect Proteins
Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Molecular Sequence Data

Motor Activity

Mutation

Nervous System

Source

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Identifiers

PMID: 10880484
DOI: 10.1093/genetics/155.3.1231
PMCID: PMC1461160

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