Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2.

doi:10.1093/genetics/148.1.251

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2.

Genetics - 1 Jan 1998

Elfring L K, Daniel C, Papoulas O, Deuring R, Sarte M, Moseley S, Beek S J, Waldrip W R, Daubresse G, DePace A, Kennison J A, Tamkun J W

Abstract excerpt

The Drosophila brahma (brm) gene encodes an activator of homeotic genes related to the yeast chromatin remodeling factor SWI2/SNF2. Here, we report the phenotype of null and dominant-negative brm mutations. Using mosaic analysis, we found that the complete loss of brm function decreases cell viab...

Topics

Amino Acid Sequence
Animals
Cell Cycle Proteins
Conserved Sequence
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Insect Proteins
Molecular Sequence Data
Mutagenesis, Site-Directed
Nuclear Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Protein Structure, Tertiary

Sequence Alignment

Sequence Homology, Amino Acid

Trans-Activators

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 9475737
DOI: 10.1093/genetics/148.1.251
PMCID: PMC1459776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9475737-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2.PMID 9475737Read ↗

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.Semantic proximity Read ↗

SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development.Semantic proximity Read ↗

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).Semantic proximity Read ↗

Genetic screens for enhancers of brahma reveal functional interactions between the BRM chromatin-remodeling complex and the delta-notch signal transduction pathway in Drosophila.Semantic proximity Read ↗

Characterization of a Brg1 hypomorphic allele demonstrates that genetic and biochemical activity are tightly correlated.Semantic proximity Read ↗

Hormone-response genes are direct in vivo regulatory targets of Brahma (SWI/SNF) complex function.Semantic proximity Read ↗

A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development.Semantic proximity Read ↗

Essential Role of ARID2 Protein-containing SWI/SNF Complex in Tissue-specific Gene ExpressionSemantic proximity Read ↗

BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?Semantic proximity Read ↗

SNR1 (INI1/SNF5) mediates important cell growth functions of the Drosophila Brahma (SWI/SNF) chromatin remodeling complex.Semantic proximity Read ↗

The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit.Semantic proximity Read ↗

The Drosophila Brahma (SWI/SNF) chromatin remodeling complex exhibits cell-type specific activation and repression functions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.